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Motoneurons Derived from Embryonic Stem Cells Express Transcription Factors and Develop Phenotypes Characteristic of Medial Motor Column Neurons

Embryonic stem (ES) cells differentiate into functional motoneurons when treated with a sonic hedgehog (Shh) agonist and retinoic acid (RA). Whether ES cells can be directed to differentiate into specific subtypes of motoneurons is unknown. We treated embryoid bodies generated from HBG3 ES cells wit...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Soundararajan, Prabakaran, Miles, Gareth B., Rubin, Lee L., Brownstone, Robert M., Rafuse, Victor F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2006
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674087/
https://ncbi.nlm.nih.gov/pubmed/16554476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5537-05.2006
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