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Motoneurons Derived from Embryonic Stem Cells Express Transcription Factors and Develop Phenotypes Characteristic of Medial Motor Column Neurons

Embryonic stem (ES) cells differentiate into functional motoneurons when treated with a sonic hedgehog (Shh) agonist and retinoic acid (RA). Whether ES cells can be directed to differentiate into specific subtypes of motoneurons is unknown. We treated embryoid bodies generated from HBG3 ES cells wit...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Soundararajan, Prabakaran, Miles, Gareth B., Rubin, Lee L., Brownstone, Robert M., Rafuse, Victor F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6674087/
https://ncbi.nlm.nih.gov/pubmed/16554476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5537-05.2006
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