Synapse-Associated Protein-97 Mediates α-Secretase ADAM10 Trafficking and Promotes Its Activity

Alzheimer's disease (AD) is a chronic neurodegenerative disorder caused by a combination of events impairing normal neuronal function. Here we found a molecular bridge between key elements of primary and secondary pathogenic events in AD, namely the elements of the amyloid cascade and synaptic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Marcello, Elena, Gardoni, Fabrizio, Mauceri, Daniela, Romorini, Stefano, Jeromin, Andreas, Epis, Roberta, Borroni, Barbara, Cattabeni, Flaminio, Sala, Carlo, Padovani, Alessandro, Di Luca, Monica
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2007
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673742/
https://ncbi.nlm.nih.gov/pubmed/17301176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3439-06.2007
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