[alpha]-Secretase ADAM10 as well as [alpha]APPs is reduced in platelets and CSF of Alzheimer disease patients.

BACKGROUND: Members of membrane-bound disintegrin metalloproteinases (ADAMs) were shown to be capable of cleaving amyloid precursor protein (APP) at the alpha-cleavage site in different cell systems. One of the candidate alpha-secretases identified in this family is ADAM10. The present study address...

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Detaylı Bibliyografya
Asıl Yazarlar: Colciaghi, Francesca, Borroni, Barbara, Pastorino, Lucia, Marcello, Elena, Zimmermann, Martina, Cattabeni, Flaminio, Padovani, Alessandro, Di Luca, Monica
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2002
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039975/
https://ncbi.nlm.nih.gov/pubmed/12080182
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