Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer’s disease

A disintegrin and metalloproteinase 10 (ADAM10), a disintegrin and metalloproteinase that resides in the postsynaptic densities (PSDs) of excitatory synapses, has previously been shown to limit β-amyloid peptide (Aβ) formation in Alzheimer’s disease (AD). ADAM10 also plays a critical role in regulat...

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Detalhes bibliográficos
Main Authors: Marcello, Elena, Saraceno, Claudia, Musardo, Stefano, Vara, Hugo, de la Fuente, Alerie Guzman, Pelucchi, Silvia, Di Marino, Daniele, Borroni, Barbara, Tramontano, Anna, Pérez-Otaño, Isabel, Padovani, Alessandro, Giustetto, Maurizio, Gardoni, Fabrizio, Di Luca, Monica
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668814/
https://ncbi.nlm.nih.gov/pubmed/23676497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65401
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