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An Arginine Stretch Limits ADAM10 Exit from the Endoplasmic Reticulum
A disintegrin and metalloproteinase 10 (ADAM10) is a type I transmembrane glycoprotein responsible for the ectodomain shedding of a number of proteins implicated in the pathogenesis of diseases ranging from cancer to Alzheimer Disease. ADAM10 is synthesized in an inactive form, which is proteolytica...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2856244/ https://ncbi.nlm.nih.gov/pubmed/20100836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.055947 |
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