Development of Hydrocephalus in Mice Expressing the G(i)-Coupled GPCR Ro1 RASSL Receptor in Astrocytes

We developed a transgenic mouse line that expresses the G(i)-coupled RASSL (receptor activated solely by synthetic ligand) Ro1 in astrocytes to study astrocyte–neuronal communication. Surprisingly, we found that all transgenics expressing Ro1 developed hydrocephalus. We analyzed these mice in an eff...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Sweger, Elizabeth J., Casper, Kristen B., Scearce-Levie, Kimberly, Conklin, Bruce R., McCarthy, Ken D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2007
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673489/
https://ncbi.nlm.nih.gov/pubmed/17329428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4565-06.2007
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