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Development of Hydrocephalus in Mice Expressing the G(i)-Coupled GPCR Ro1 RASSL Receptor in Astrocytes
We developed a transgenic mouse line that expresses the G(i)-coupled RASSL (receptor activated solely by synthetic ligand) Ro1 in astrocytes to study astrocyte–neuronal communication. Surprisingly, we found that all transgenics expressing Ro1 developed hydrocephalus. We analyzed these mice in an eff...
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| Publicado en: | J Neurosci |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for Neuroscience
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6673489/ https://ncbi.nlm.nih.gov/pubmed/17329428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4565-06.2007 |
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