Isoform-Selective Susceptibility of DISC1/Phosphodiesterase-4 Complexes to Dissociation by Elevated Intracellular cAMP Levels

Disrupted-in-schizophrenia 1 (DISC1) is a genetic susceptibility factor for schizophrenia and related severe psychiatric conditions. DISC1 is a multifunctional scaffold protein that is able to interact with several proteins, including the independently identified schizophrenia risk factor phosphodie...

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Publié dans:J Neurosci
Auteurs principaux: Murdoch, Hannah, Mackie, Shaun, Collins, Daniel M., Hill, Elaine V., Bolger, Graeme B., Klussmann, Enno, Porteous, David J., Millar, J. Kirsty, Houslay, Miles D.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2007
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673124/
https://ncbi.nlm.nih.gov/pubmed/17728464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1493-07.2007
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