Excessive Activation of Poly(ADP-Ribose) Polymerase Contributes to Inherited Photoreceptor Degeneration in the Retinal Degeneration 1 Mouse

Retinitis pigmentosa (RP) is an inherited blinding disease for which there is no treatment available. It is characterized by a progressive and neurodegenerative loss of photoreceptors but the underlying mechanisms are poorly understood. Excessive activation of the enzyme poly(ADP-ribose) polymerase...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Paquet-Durand, François, Silva, José, Talukdar, Tanuja, Johnson, Leif E., Azadi, Seifollah, van Veen, Theo, Ueffing, Marius, Hauck, Stefanie M., Ekström, Per A. R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672664/
https://ncbi.nlm.nih.gov/pubmed/17881537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1514-07.2007
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