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The cGMP Pathway and Inherited Photoreceptor Degeneration: Targets, Compounds, and Biomarkers

Photoreceptor physiology and pathophysiology is intricately linked to guanosine-3’,5’-cyclic monophosphate (cGMP)-signaling. Here, we discuss the importance of cGMP-signaling for the pathogenesis of hereditary retinal degeneration. Excessive accumulation of cGMP in photoreceptors is a common denomin...

詳細記述

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書誌詳細
出版年:Genes (Basel)
主要な著者: Tolone, Arianna, Belhadj, Soumaya, Rentsch, Andreas, Schwede, Frank, Paquet-Durand, François
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6627777/
https://ncbi.nlm.nih.gov/pubmed/31207907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10060453
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