Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptors

Hereditary retinal degeneration (RD) relates to a heterogeneous group of blinding human diseases in which the light sensitive neurons of the retina, the photoreceptors, die. RD is currently untreatable and the underlying cellular mechanisms remain poorly understood. However, the activity of the enzy...

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Detalhes bibliográficos
Main Authors: Sahaboglu, A, Tanimoto, N, Bolz, S, Garrido, M G, Ueffing, M, Seeliger, M W, Löwenheim, H, Ekström, P, Paquet-Durand, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047865/
https://ncbi.nlm.nih.gov/pubmed/24853412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.208
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