Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptors

Hereditary retinal degeneration (RD) relates to a heterogeneous group of blinding human diseases in which the light sensitive neurons of the retina, the photoreceptors, die. RD is currently untreatable and the underlying cellular mechanisms remain poorly understood. However, the activity of the enzy...

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Bibliografiske detaljer
Main Authors: Sahaboglu, A, Tanimoto, N, Bolz, S, Garrido, M G, Ueffing, M, Seeliger, M W, Löwenheim, H, Ekström, P, Paquet-Durand, F
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047865/
https://ncbi.nlm.nih.gov/pubmed/24853412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.208
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