Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptors

Hereditary retinal degeneration (RD) relates to a heterogeneous group of blinding human diseases in which the light sensitive neurons of the retina, the photoreceptors, die. RD is currently untreatable and the underlying cellular mechanisms remain poorly understood. However, the activity of the enzy...

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Detaylı Bibliyografya
Asıl Yazarlar: Sahaboglu, A, Tanimoto, N, Bolz, S, Garrido, M G, Ueffing, M, Seeliger, M W, Löwenheim, H, Ekström, P, Paquet-Durand, F
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047865/
https://ncbi.nlm.nih.gov/pubmed/24853412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.208
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