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Swimming against the Tide: Mobility of the Microtubule-Associated Protein Tau in Neurons
Long-haul transport along microtubules is crucial for neuronal polarity, and transport defects cause neurodegeneration. Tau protein stabilizes microtubule tracks, but in Alzheimer's disease it aggregates and becomes missorted into the somatodendritic compartment. Tau can inhibit axonal transpor...
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| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6672630/ https://ncbi.nlm.nih.gov/pubmed/17855606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0927-07.2007 |
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