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Swimming against the Tide: Mobility of the Microtubule-Associated Protein Tau in Neurons

Long-haul transport along microtubules is crucial for neuronal polarity, and transport defects cause neurodegeneration. Tau protein stabilizes microtubule tracks, but in Alzheimer's disease it aggregates and becomes missorted into the somatodendritic compartment. Tau can inhibit axonal transpor...

詳細記述

保存先:
書誌詳細
出版年:J Neurosci
主要な著者: Konzack, Sven, Thies, Edda, Marx, Alexander, Mandelkow, Eva-Maria, Mandelkow, Eckhard
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672630/
https://ncbi.nlm.nih.gov/pubmed/17855606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0927-07.2007
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