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Fragile X Mental Retardation Protein Induces Synapse Loss through Acute Postsynaptic Translational Regulation

Fragile X syndrome, as well as other forms of mental retardation and autism, is associated with altered dendritic spine number and structure. Fragile X syndrome is caused by loss-of-function mutations in Fragile X mental retardation protein (FMRP), an RNA-binding protein that regulates protein synth...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Pfeiffer, Brad E., Huber, Kimberly M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672463/
https://ncbi.nlm.nih.gov/pubmed/17376973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0054-07.2007
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