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Multiple Gq-Coupled Receptors Converge on a Common Protein Synthesis-Dependent Long-Term Depression That Is Affected in Fragile X Syndrome Mental Retardation

Gq-coupled, M(1) muscarinic acetylcholine receptors (mAChRs) facilitate hippocampal learning, memory, and synaptic plasticity. M(1) mAChRs induce long-term synaptic depression (LTD), but little is known about the underlying mechanisms of mAChR-dependent LTD and its link to cognitive function. Here,...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Volk, Lenora J., Pfeiffer, Brad E., Gibson, Jay R., Huber, Kimberly M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673232/
https://ncbi.nlm.nih.gov/pubmed/17959805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2266-07.2007
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