Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses

Fragile X mental retardation is caused by absence of the RNA-binding protein fragile X mental retardation protein (FMRP), encoded by the FMR1 gene. There is increasing evidence that FMRP regulates transport and modulates translation of some mRNAs. We studied neurotransmitter-activated synaptic prote...

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Main Authors: Weiler, Ivan Jeanne, Spangler, Chad C., Klintsova, Anna Y., Grossman, Aaron W., Kim, Soong Ho, Bertaina-Anglade, Valerie, Khaliq, Hooma, de Vries, Froukje E., Lambers, Femke A. E., Hatia, Fatima, Base, Christine K., Greenough, William T.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2004
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC536018/
https://ncbi.nlm.nih.gov/pubmed/15548614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407533101
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