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Altered mRNA transport, docking, and protein translation in neurons lacking fragile X mental retardation protein

Fragile X syndrome is caused by the absence of functional fragile X mental retardation protein (FMRP), an RNA binding protein. The molecular mechanism of aberrant protein synthesis in fmr1 KO mice is closely associated with the role of FMRP in mRNA transport, delivery, and local protein synthesis. W...

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Bibliografische gegevens
Hoofdauteurs: Kao, Der-I, Aldridge, Georgina M., Weiler, Ivan Jeanne, Greenough, William T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932564/
https://ncbi.nlm.nih.gov/pubmed/20713728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010564107
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