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Altered mRNA transport, docking, and protein translation in neurons lacking fragile X mental retardation protein
Fragile X syndrome is caused by the absence of functional fragile X mental retardation protein (FMRP), an RNA binding protein. The molecular mechanism of aberrant protein synthesis in fmr1 KO mice is closely associated with the role of FMRP in mRNA transport, delivery, and local protein synthesis. W...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2932564/ https://ncbi.nlm.nih.gov/pubmed/20713728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010564107 |
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