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Slow Conformational Changes of the Voltage Sensor during the Mode Shift in Hyperpolarization-Activated Cyclic-Nucleotide-Gated Channels

Hyperpolarization-activated cyclic-nucleotide-gated (HCN) channels are activated by hyperpolarizations that cause inward movements of the positive charges in the fourth transmembrane domain (S4), which triggers channel opening. If HCN channels are held open for prolonged times (>50 ms), HCN chann...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Bruening-Wright, Andrew, Larsson, H. Peter
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672073/
https://ncbi.nlm.nih.gov/pubmed/17215386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3801-06.2007
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