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Slow Conformational Changes of the Voltage Sensor during the Mode Shift in Hyperpolarization-Activated Cyclic-Nucleotide-Gated Channels

Hyperpolarization-activated cyclic-nucleotide-gated (HCN) channels are activated by hyperpolarizations that cause inward movements of the positive charges in the fourth transmembrane domain (S4), which triggers channel opening. If HCN channels are held open for prolonged times (>50 ms), HCN chann...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bruening-Wright, Andrew, Larsson, H. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672073/
https://ncbi.nlm.nih.gov/pubmed/17215386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3801-06.2007
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