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Kinetic Relationship between the Voltage Sensor and the Activation Gate in spHCN Channels

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are activated by membrane hyperpolarizations that cause an inward movement of the positive charges in the fourth transmembrane domain (S4), which triggers channel opening. The mechanism of how the motion of S4 charges triggers channe...

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Detalhes bibliográficos
Main Authors: Bruening-Wright, Andrew, Elinder, Fredrik, Larsson, H. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154369/
https://ncbi.nlm.nih.gov/pubmed/17591986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709769
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