ABCA1- and ABCG1-mediated cholesterol efflux capacity of cerebrospinal fluid is impaired in Alzheimer’s disease

HDL-like particles in human cerebrospinal fluid (CSF) promote the efflux of cholesterol from astrocytes toward the neurons that rely on this supply for their functions. We evaluated whether cell cholesterol efflux capacity of CSF (CSF-CEC) is impaired in Alzheimer’s disease (AD) by analyzing AD (n =...

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Detaylı Bibliyografya
Yayımlandı:J Lipid Res
Asıl Yazarlar: Marchi, Cinzia, Adorni, Maria Pia, Caffarra, Paolo, Ronda, Nicoletta, Spallazzi, Marco, Barocco, Federica, Galimberti, Daniela, Bernini, Franco, Zimetti, Francesca
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Biochemistry and Molecular Biology 2019
Konular:
Patient-Oriented and Epidemiological Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6672040/
https://ncbi.nlm.nih.gov/pubmed/31167810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P091033
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