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Nociceptin Receptor Impairs Recognition Memory via Interaction with NMDA Receptor-Dependent Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling in the Hippocampus

Strong evidence suggests a role for nociceptin/orphanin FQ (N/OFQ) neuropeptide and its receptor (NOP) in cognition. However, the signaling mechanisms underlying N/OFQ modulation of memory are less understood. Here, we show that intracerebroventricular or intrahippocampal infusions of N/OFQ impair l...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Goeldner, Celia, Reiss, David, Wichmann, Jürgen, Meziane, Hamid, Kieffer, Brigitte L., Ouagazzal, Abdel-Mouttalib
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671849/
https://ncbi.nlm.nih.gov/pubmed/18305252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3711-07.2008
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