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Endogenous Nociceptin/Orphanin-FQ in the Dorsal Hippocampus Facilitates Despair-Related Behavior

Nociceptin/orphanin-FQ (N/OFQ) peptide and its receptor (NOP: N/OFQ opioid peptide receptor) are highly expressed in the hippocampus, but their functional role remains poorly understood. We recently showed that hippocampal N/OFQ inhibits learning and memory abilities in mice. Here, we investigated w...

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Detalhes bibliográficos
Publicado no:Hippocampus
Main Authors: Goeldner, Celia, Reiss, David, Kieffer, Brigitte L., Ouagazzal, Abdel-Mouttalib
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494786/
https://ncbi.nlm.nih.gov/pubmed/20087887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20760
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