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The Activation Gate and Gating Mechanism of the NMDA Receptor

The NMDA receptor opens in response to binding of NMDA and glycine. However, it remains unclear where and how gating of the NMDA receptor pore is accomplished. We show that different point mutations between S645 and I655 (thus including the highly conserved SYTANLAAF motif) of M3c in NR2B lead to co...

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Publicat a:J Neurosci
Autors principals: Chang, Huai-Ren, Kuo, Chung-Chin
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671534/
https://ncbi.nlm.nih.gov/pubmed/18272676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3485-07.2008
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