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The Activation Gate and Gating Mechanism of the NMDA Receptor

The NMDA receptor opens in response to binding of NMDA and glycine. However, it remains unclear where and how gating of the NMDA receptor pore is accomplished. We show that different point mutations between S645 and I655 (thus including the highly conserved SYTANLAAF motif) of M3c in NR2B lead to co...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Chang, Huai-Ren, Kuo, Chung-Chin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671534/
https://ncbi.nlm.nih.gov/pubmed/18272676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3485-07.2008
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