Mechanism of NMDA receptor inhibition and activation

N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated, calcium-permeable ion channels that mediate synaptic transmission and underpin learning and memory. NMDAR dysfunction is directly implicated in diseases ranging from seizure to ischemia. Despite its fundamental importance, little is known...

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Bibliografische gegevens
Gepubliceerd in:Cell
Hoofdauteurs: Zhu, Shujia, Stein, Richard A., Yoshioka, Craig, Lee, Chia-Hsueh, Goehring, April, Mchaourab, Hassane S., Gouaux, Eric
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914038/
https://ncbi.nlm.nih.gov/pubmed/27062927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.03.028
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