Amyloid β Oligomers (Aβ(1–42) Globulomer) Suppress Spontaneous Synaptic Activity by Inhibition of P/Q-Type Calcium Currents

Abnormal accumulation of soluble oligomers of amyloid β (Aβ) is believed to cause malfunctioning of neurons in Alzheimer's disease. It has been shown that Aβ oligomers impair synaptic plasticity, thereby altering the ability of the neuron to store information. We examined the underlying cellula...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Nimmrich, Volker, Grimm, Christiane, Draguhn, Andreas, Barghorn, Stefan, Lehmann, Alexander, Schoemaker, Hans, Hillen, Heinz, Gross, Gerhard, Ebert, Ulrich, Bruehl, Claus
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2008
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6671006/
https://ncbi.nlm.nih.gov/pubmed/18216187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4771-07.2008
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