A β-amyloid oligomer directly modulates P/Q-type calcium currents in Xenopus oocytes

BACKGROUND AND PURPOSE: β-amyloid (Aβ) oligomers have been implicated in the early pathophysiology of Alzheimer's disease (AD). While the precise nature of the molecular target has not been fully revealed, a number of studies have indicated that Aβ oligomers modulate neuron-specific ion channel...

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Bibliographic Details
Main Authors: Mezler, M, Barghorn, S, Schoemaker, H, Gross, G, Nimmrich, V
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2012
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372738/
https://ncbi.nlm.nih.gov/pubmed/21883149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01646.x
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