In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons

Accumulation of neurofibrillary tangles (NFTs) in Alzheimer's disease correlates with neuronal loss and cognitive decline, but the precise relationship between NFTs and neuronal death and downstream mechanisms of cell death remain unclear. Caspase cleaved products accumulate in tangles, implyin...

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書目詳細資料
發表在:J Neurosci
Main Authors: Spires-Jones, Tara L., de Calignon, Alix, Matsui, Toshifumi, Zehr, Cindy, Pitstick, Rose, Wu, Hai-Yan, Osetek, Jennifer D., Jones, Phillip B., Bacskai, Brian J., Feany, Mel B., Carlson, George A., Ashe, Karen H., Lewis, Jada, Hyman, Bradley T.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2008
主題:
Brief Communications
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670992/
https://ncbi.nlm.nih.gov/pubmed/18216194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3072-08.2008
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