In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons

Accumulation of neurofibrillary tangles (NFTs) in Alzheimer's disease correlates with neuronal loss and cognitive decline, but the precise relationship between NFTs and neuronal death and downstream mechanisms of cell death remain unclear. Caspase cleaved products accumulate in tangles, implyin...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Spires-Jones, Tara L., de Calignon, Alix, Matsui, Toshifumi, Zehr, Cindy, Pitstick, Rose, Wu, Hai-Yan, Osetek, Jennifer D., Jones, Phillip B., Bacskai, Brian J., Feany, Mel B., Carlson, George A., Ashe, Karen H., Lewis, Jada, Hyman, Bradley T.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670992/
https://ncbi.nlm.nih.gov/pubmed/18216194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3072-08.2008
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