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Cyclin-Dependent Kinase 5 Supports Neuronal Survival through Phosphorylation of Bcl-2

Accumulating evidence indicates that deregulation of cyclin-dependent kinase 5 (Cdk5) activity is associated with apoptosis in various neurodegenerative disease models. Interestingly, recent studies suggest that Cdk5 may also favor neuronal survival. Nonetheless, whether Cdk5 is directly required fo...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Cheung, Zelda H., Gong, Ke, Ip, Nancy Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670728/
https://ncbi.nlm.nih.gov/pubmed/18463240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0689-08.2008
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