Phosphorylation of Drebrin by Cyclin-Dependent Kinase 5 and Its Role in Neuronal Migration

Cyclin-dependent kinase 5 (Cdk5)-p35 is a proline-directed Ser/Thr kinase which plays a key role in neuronal migration, neurite outgrowth, and spine formation during brain development. Dynamic remodeling of cytoskeletons is required for all of these processes. Cdk5-p35 phosphorylates many cytoskelet...

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Main Authors: Tanabe, Kazuya, Yamazaki, Hiroyuki, Inaguma, Yutaka, Asada, Akiko, Kimura, Taeko, Takahashi, Junya, Taoka, Masato, Ohshima, Toshio, Furuichi, Teiichi, Isobe, Toshiaki, Nagata, Koh-ichi, Shirao, Tomoaki, Hisanaga, Shin-ichi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3956921/
https://ncbi.nlm.nih.gov/pubmed/24637538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092291
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