Neuronal Cyclin-Dependent Kinase 5 Activity Is Critical for Survival

Cyclin-dependent kinase 5 (Cdk5) null mice exhibit a unique phenotype characterized by perinatal mortality, disrupted cerebral cortical layering attributable to abnormal neuronal migration, lack of cerebellar foliation, and chromatolytic changes of neurons in the brainstem and the spinal cord. Becau...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Tanaka, Teruyuki, Veeranna, Ohshima, Toshio, Rajan, Prithi, Amin, Niranjana D., Cho, Andrew, Sreenath, Taduru, Pant, Harish C., Brady, Roscoe O., Kulkarni, Ashok B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763824/
https://ncbi.nlm.nih.gov/pubmed/11160434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-02-00550.2001
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