PCTAIRE Kinase 3/Cyclin-dependent Kinase 18 Is Activated through Association with Cyclin A and/or Phosphorylation by Protein Kinase A

PCTAIRE kinase 3 (PCTK3)/cyclin-dependent kinase 18 (CDK18) is an uncharacterized member of the CDK family because its activator(s) remains unidentified. Here we describe the mechanisms of catalytic activation of PCTK3 by cyclin A2 and cAMP-dependent protein kinase (PKA). Using a pulldown experiment...

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Detaylı Bibliyografya
Asıl Yazarlar: Matsuda, Shinya, Kominato, Kyohei, Koide-Yoshida, Shizuyo, Miyamoto, Kenji, Isshiki, Kinuka, Tsuji, Akihiko, Yuasa, Keizo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140294/
https://ncbi.nlm.nih.gov/pubmed/24831015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.542936
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