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PCTK3/CDK18 regulates cell migration and adhesion by negatively modulating FAK activity

PCTAIRE kinase 3 (PCTK3) is a member of the cyclin dependent kinase family, but its physiological function remains unknown. We previously reported that PCTK3-knockdown HEK293T cells showed actin accumulation at the leading edge, suggesting that PCTK3 is involved in the regulation of actin reorganiza...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matsuda, Shinya, Kawamoto, Kohei, Miyamoto, Kenji, Tsuji, Akihiko, Yuasa, Keizo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374530/
https://ncbi.nlm.nih.gov/pubmed/28361970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45545
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