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The Mitochondrial Protease AFG3L2 Is Essential for Axonal Development

The mitochondrial metalloprotease AFG3L2 assembles with the homologous protein paraplegin to form a supracomplex in charge of the essential protein quality control within mitochondria. Mutations of paraplegin cause a specific axonal degeneration of the upper motoneuron and, therefore, hereditary spa...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Maltecca, Francesca, Aghaie, Asadollah, Schroeder, David G., Cassina, Laura, Taylor, Benjamin A., Phillips, Sandra J., Malaguti, Mariachiara, Previtali, Stefano, Guénet, Jean-Louis, Quattrini, Angelo, Cox, Gregory A., Casari, Giorgio
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2008
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670688/
https://ncbi.nlm.nih.gov/pubmed/18337413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4677-07.2008
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