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Axonal degeneration in paraplegin-deficient mice is associated with abnormal mitochondria and impairment of axonal transport
In several neurodegenerative diseases, axonal degeneration occurs before neuronal death and contributes significantly to patients’ disability. Hereditary spastic paraplegia (HSP) is a genetically heterogeneous condition characterized by selective degeneration of axons of the corticospinal tracts and...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2004
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC311437/ https://ncbi.nlm.nih.gov/pubmed/14722615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420138 |
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