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Dissecting substrate specificities of the mitochondrial AFG3L2 protease

Human AFG3L2 is a compartmental AAA+ protease that performs ATP-fueled degradation at the matrix face of the inner mitochondrial membrane. Identifying how AFG3L2 selects substrates from the diverse complement of matrix-localized proteins is essential for understanding mitochondrial protein biogenesi...

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Publicat a:Biochemistry
Autors principals: Ding, Bojian, Martin, Dwight W., Rampello, Anthony J., Glynn, Steven E.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475807/
https://ncbi.nlm.nih.gov/pubmed/29932645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00565
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