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Engineered AAA+ proteases reveal principles of proteolysis at the mitochondrial inner membrane
The human YME1L protease is a membrane-anchored AAA+ enzyme that controls proteostasis at the inner membrane and intermembrane space of mitochondria. Understanding how YME1L recognizes substrates and catalyses ATP-dependent degradation has been hampered by the presence of an insoluble transmembrane...
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| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5095350/ https://ncbi.nlm.nih.gov/pubmed/27786171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13301 |
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