Absence of Functional Peroxisomes from Mouse CNS Causes Dysmyelination and Axon Degeneration

Peroxisomal metabolism is essential for normal brain development both in men and in mice. Using conditional knock-out mice, we recently showed that peroxisome deficiency in liver has a severe and persistent impact on the formation of cortex and cerebellum, whereas absence of functional peroxisomes f...

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Vydáno v:J Neurosci
Hlavní autoři: Hulshagen, Leen, Krysko, Olga, Bottelbergs, Astrid, Huyghe, Steven, Klein, Rüdiger, Van Veldhoven, Paul P., De Deyn, Peter P., D'Hooge, Rudi, Hartmann, Dieter, Baes, Myriam
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670456/
https://ncbi.nlm.nih.gov/pubmed/18400901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4968-07.2008
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