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Peroxisomal Multifunctional Protein-2 Deficiency Causes Motor Deficits and Glial Lesions in the Adult Central Nervous System
In humans, mutations inactivating multifunctional protein-2 (MFP-2), and thus peroxisomal β-oxidation, cause neuronal heterotopia and demyelination, which is clinically reflected by hypotonia, seizures, and death within the first year of life. In contrast, our recently generated MFP-2-deficient mice...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1606565/ https://ncbi.nlm.nih.gov/pubmed/16565505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.041220 |
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