Microglia lacking a peroxisomal β-oxidation enzyme chronically alter their inflammatory profile without evoking neuronal and behavioral deficits

BACKGROUND: Microglia play a central role in most neurological disorders, but the impact of microgliosis on brain environment and clinical functions is not fully understood. Mice lacking multifunctional protein-2 (MFP2), a pivotal enzyme in peroxisomal β-oxidation, develop a fatal disorder character...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Beckers, Lien, Geric, Ivana, Stroobants, Stijn, Beel, Sander, Van Damme, Philip, D’Hooge, Rudi, Baes, Myriam
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417251/
https://ncbi.nlm.nih.gov/pubmed/30866963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1442-3
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