Transforming Growth Factor-β1 Decreases β(2)-Agonist–induced Relaxation in Human Airway Smooth Muscle

Helper T effector cytokines implicated in asthma modulate the contractility of human airway smooth muscle (HASM) cells. We have reported recently that a profibrotic cytokine, transforming growth factor (TGF)-β1, induces HASM cell shortening and airway hyperresponsiveness. Here, we assessed whether T...

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Vydáno v:Am J Respir Cell Mol Biol
Hlavní autoři: Ojiaku, Christie A., Chung, Elena, Parikh, Vishal, Williams, Jazmean K., Schwab, Anthony, Fuentes, Ana Lucia, Corpuz, Maia L., Lui, Victoria, Paek, Sam, Bexiga, Natalia M., Narayan, Shreya, Nunez, Francisco J., Ahn, Kwangmi, Ostrom, Rennolds S., An, Steven S., Panettieri, Reynold A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670035/
https://ncbi.nlm.nih.gov/pubmed/30742476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0301OC
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