Transforming Growth Factor-β1 Decreases β(2)-Agonist–induced Relaxation in Human Airway Smooth Muscle

Helper T effector cytokines implicated in asthma modulate the contractility of human airway smooth muscle (HASM) cells. We have reported recently that a profibrotic cytokine, transforming growth factor (TGF)-β1, induces HASM cell shortening and airway hyperresponsiveness. Here, we assessed whether T...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Ojiaku, Christie A., Chung, Elena, Parikh, Vishal, Williams, Jazmean K., Schwab, Anthony, Fuentes, Ana Lucia, Corpuz, Maia L., Lui, Victoria, Paek, Sam, Bexiga, Natalia M., Narayan, Shreya, Nunez, Francisco J., Ahn, Kwangmi, Ostrom, Rennolds S., An, Steven S., Panettieri, Reynold A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6670035/
https://ncbi.nlm.nih.gov/pubmed/30742476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0301OC
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