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Accelerating the Throughput of Affinity Mass Spectrometry-Based Ligand Screening toward a G Protein-Coupled Receptor
Affinity mass spectrometry (MS) enables rapid screening of compound mixtures for ligands bound to a specific protein target, yet its current throughput is limited to individually assay pools of 400−2000 compounds. Typical affinity MS screens implemented in pharmaceutical industry laboratories identi...
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| Опубликовано в: : | Anal Chem |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6669887/ https://ncbi.nlm.nih.gov/pubmed/31094506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b00477 |
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