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GSK3β-mediated Keap1-independent regulation of Nrf2 antioxidant response: A molecular rheostat of acute kidney injury to chronic kidney disease transition

Transition of acute kidney injury (AKI) to chronic kidney disease (CKD) represents an important cause of kidney failure. However, how AKI is transformed into CKD remains elusive. Following folic acid injury, mice developed AKI with ensuing CKD transition, featured by variable degrees of interstitial...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Lu, Minglei, Wang, Pei, Qiao, Yingjin, Jiang, Chunming, Ge, Yan, Flickinger, Bryce, Malhotra, Deepak K., Dworkin, Lance D., Liu, Zhangsuo, Gong, Rujun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669347/
https://ncbi.nlm.nih.gov/pubmed/31349118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101275
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