GSK3β-mediated Keap1-independent regulation of Nrf2 antioxidant response: A molecular rheostat of acute kidney injury to chronic kidney disease transition

Transition of acute kidney injury (AKI) to chronic kidney disease (CKD) represents an important cause of kidney failure. However, how AKI is transformed into CKD remains elusive. Following folic acid injury, mice developed AKI with ensuing CKD transition, featured by variable degrees of interstitial...

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Veröffentlicht in:Redox Biol
Hauptverfasser: Lu, Minglei, Wang, Pei, Qiao, Yingjin, Jiang, Chunming, Ge, Yan, Flickinger, Bryce, Malhotra, Deepak K., Dworkin, Lance D., Liu, Zhangsuo, Gong, Rujun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Method article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669347/
https://ncbi.nlm.nih.gov/pubmed/31349118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101275
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