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Redox-sensitive glycogen synthase kinase 3β directed control of mitochondrial permeability transition: Rheostatic regulation of acute kidney injury

Mitochondrial dysfunction plays a pivotal role in necroapoptotic cell death and in the development of acute kidney injury (AKI). Evidence suggests that glycogen synthase kinase (GSK) 3β resides at the nexus of multiple signaling pathways implicated in the regulation of mitochondrial permeability tra...

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Detalhes bibliográficos
Main Authors: Wang, Zhen, Ge, Yan, Bao, Hui, Dworkin, Lance, Peng, Ai, Gong, Rujun
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859848/
https://ncbi.nlm.nih.gov/pubmed/23973862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.08.169
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